After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!

Pedido rápido

CD68 Anticuerpo, Pabs de conejo, Purificación por afinidad con antígenos

Hoja de datosReseñasProductos relacionadosProtocolos
Human CD68 Información de producto de anticuerpo
Inmunogen:Recombinant Human CD68 protein (Catalog#11192-H08B1)
Clone ID:
Tipo de Ig:Rabbit IgG
Concentración:
Endotoxina:
Formulación:0.2 μm filtered solution in PBS with 5% trehalose
Preparación:Produced in rabbits immunized with purified, recombinant Human CD68 (rh CD68; Catalog#11192-H08B1; P34810-1; Met1-Ser319). CD68 specific IgG was purified by Human CD68 affinity chromatography.
Human CD68 Guía de uso de anticuerpo
Especificidad:Human CD68
Aplicación:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CD68. The detection limit for Human CD68 is approximately 0.00245 ng/well.

IHC-P: 0.05-2 μg/mL

Almacenamiento:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human CD68 Antibody IHC Application Image
CD68 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Hacer clic para ampliar la imagen]
Caption:
Immunochemical staining of human CD68 in human liver (cirrhosis) with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections).
CD68 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Hacer clic para ampliar la imagen]
Caption:
Immunochemical staining of human CD68 in human lung with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to macrophages.
Other CD68 Antibody Products
CD68 Fondo

Macrosialin, also known as CD68 and Gp110, is a single-pass type I  membrane protein which belongs to the LAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Human CD68 Referencias
  • Strobl H. et al., 1995, Br J Haematol. 90 (4): 774-82.
  • Ogawa Y. et al., 1995, Pathol Int. 45 (9): 698-701.
  • Sadovnikova E. et al., 2002,Leukemia. 16 (10): 2019-26.
  • Gottfried E. et al., 2008, Scand J Immunol. 67 (5): 453-63.
  • Strojnik T. et al., 2009, Anticancer Res. 29 (8): 3269-79.
  • Product nameProduct name
    Size / Price
    Catálogo: 11192-RP02-50
    Precio de lista: 
    Precio:      (You Save: )
    Tamaño:
    50 µg
    100 µg
    200 µg
    Cantidad:+-
    DisponibilidadIn Stock
    Bulk Discount RequiryAñadir a carro
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Nota: Todos los productos son "PARA SU USO ÚNICAMENTE EN INVESTIGACIÓN Y NO INDICADOS PARA SU USO DIAGNÓSTICO O TERAPÉUTICO"