|Hoja de datos||Reseñas||Productos relacionados||Protocolos|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.
|Canine CLU ORF mammalian expression plasmid, C-GFPSpark tag||DG70207-ACG|
|Canine CLU ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70207-ACR|
|Canine CLU ORF mammalian expression plasmid, C-Flag tag||DG70207-CF|
|Canine CLU ORF mammalian expression plasmid, C-His tag||DG70207-CH|
|Canine CLU ORF mammalian expression plasmid, C-Myc tag||DG70207-CM|
|Canine CLU ORF mammalian expression plasmid, C-HA tag||DG70207-CY|
|Canine CLU ORF mammalian expression plasmid, N-Flag tag||DG70207-NF|
|Canine CLU ORF mammalian expression plasmid, N-His tag||DG70207-NH|
|Canine CLU ORF mammalian expression plasmid, N-Myc tag||DG70207-NM|
|Canine CLU ORF mammalian expression plasmid, N-HA tag||DG70207-NY|
|Canine CLU Gene cDNA clone plasmid||DG70207-U|
|Canine CLU natural ORF mammalian expression plasmid||DG70207-UT|
|Más información sobre los vectores de expresión|
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.