Pedido rápido

Endoglin / CD105 / ENG Anticuerpo, Pabs de conejo, Purificación por afinidad con antígenos

  • Endoglin / CD105 / ENG Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • Endoglin / CD105 / ENG Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
  • Endoglin / CD105 / ENG Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Hoja de datosReseñasProductos relacionadosProtocolos
Humano ENG Información de producto de anticuerpo
Inmunogen:A synthetic peptide corresponding to the center region of the Human CD105.
Clone ID:
Tipo de Ig:Rabbit IgG
Concentración:
Endotoxina:
Formulación:0.2 μm filtered solution in PBS with 5% trehalose
Preparación:Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human CD105, and purified by antigen affinity chromatography.
Other ENG Antibody Products
Endoglin/CD105  Fondo

Endoglin, also known as CD105, is a type I  homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD tripeptide which is a key recognition structure in cellular adhesion,,suggesting a critical role for endoglin in the binding of endothelial cells to integrins and/or other RGD receptors. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages. As an accessory receptor for the TGF-β superfamily ligands, endoglin binds TGF-β1 and TGF-β3 with high affinity not by itself but by associating with TGF-β type I I receptor (TβRII) and activates the downstream signal pathways. In addition, in human umbilical vein endothelial cells, ALK-1 is also a receptor kinase for endoglin threonine phosphorylation, and mutations in either of the two genes result in the autosomal-dominant vascular dysplasia, hereditary hemorrhagic telangiectasia (HHT). Endoglin has been regarded as a powerful biomarker of neovascularization, and is associated with several solid tumor types.

Product nameProduct name
Size / Price
Catálogo: 100088-RP02-50
Precio de lista: 
Precio:      (You Save: )
Tamaño:
50 µg
100 µg
200 µg
Cantidad:+-
DisponibilidadIn Stock
Añadir a carroBulk Discount Requiry

Datasheet & Documentation

All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
Nota: Todos los productos son "PARA SU USO ÚNICAMENTE EN INVESTIGACIÓN Y NO INDICADOS PARA SU USO DIAGNÓSTICO O TERAPÉUTICO"