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IL-3 Anticuerpo, Pabs de conejo, Purificación por afinidad con antígenos

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Rat IL3 Información de producto de anticuerpo
Inmunogen:Recombinant Rat IL-3 protein (Catalog#80235-R08B)
Clone ID:
Tipo de Ig:Rabbit IgG
Concentración:
Endotoxina:
Formulación:0.2 μm filtered solution in PBS with 5% trehalose
Preparación:Produced in rabbits immunized with purified, recombinant Rat IL-3 (rR IL-3; Catalog#80235-R08B; NP_113701.1; Met1-Cys169). IL-3 specific IgG was purified by Rat IL-3 affinity chromatography.
Rat IL3 Guía de uso de anticuerpo
Especificidad:Rat IL-3
Aplicación:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat IL-3. The detection limit for Rat IL-3 is approximately 0.00975 ng/well.

IHC-P: 0.1-2 μg/mL

Almacenamiento:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Rat IL3 Antibody IHC Application Image
IL-3 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Hacer clic para ampliar la imagen]
Caption:
Immunochemical staining of rat IL3 in rat spleen with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other IL3 Antibody Products
IL3/IL-3/Interleukin-3 Fondo

IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Rat IL3/IL-3/Interleukin-3 Referencias
  • Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
  • Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
  • Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.
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    Nota: Todos los productos son "PARA SU USO ÚNICAMENTE EN INVESTIGACIÓN Y NO INDICADOS PARA SU USO DIAGNÓSTICO O TERAPÉUTICO"