Integrin beta 3 (Protein | Antibody | cDNA Clone | ELISA Kit)

All Integrin beta 3 reagents are produced in house and quality controlled, including 3 Integrin beta 3 Antibody, 52 Integrin beta 3 Gene, 3 Integrin beta 3 qPCR. All Integrin beta 3 reagents are ready to use.

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Integrin beta 3 Background

Integrins containing the beta(3) subunit are key players in tumor growth and metastasis.ITGB3 plays an important role in ROS-induced migration and invasion in Colorectal cancer (CRC).ITGB3 is translationally activated in hypoxia and regulates malignant features, including epithelial-mesenchymal transition and cell migration, through the TGF-beta pathway, revealing a novel angle for the treatment of therapy-resistant hypoxic tumours.Bioinformatic algorithms and luciferase reporter assays revealed that integrin beta3 (ITGB3) is a direct target of miR-3a-5p.