p67phox cDNA ORF Clone, Mouse, untagged General Information
Full length Clone DNA of Mouse neutrophil cytosolic factor 2.
Enhanced CMV promoter
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
p67phox cDNA ORF Clone, Mouse, untagged Alternative Names
Ncf-2 cDNA ORF Clone, Mouse;NOXA2 cDNA ORF Clone, Mouse;p67phox cDNA ORF Clone, Mouse
p67phox Background Information
NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.
neutrophil cytosolic factor 2
Wientjes FB. et al., 1996, Semin Cell Biol. 6 (6): 357-65. DeLeo FR. et al., 1997, J Leukoc Biol. 60 (6): 677-91. Dorseuil O. et al., 1997, C R Seances Soc Biol Fil. 191 (2): 237-46.