uPAR qPCR Primer Pairs, Mouse

Cat: MP200190

Contact us:

215-583-7898
order_us@sinobiological.com
Distributors

All uPAR Reagents

CRO Services

Product recommended


All uPAR Reagents

uPAR qPCR Primer Pairs, Mouse General Information

Target Details

Species:
Mouse

Product Details

Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.

Application & Quality

Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.

Storage & Shipping

Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages

Unique Primer Design

To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.

Strict Validation Process

Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.

Uniform PCR conditions, Saving time and cost

~100% amplification curve, ensuring the accuracy of the RNA quantitative

uPAR qPCR Primer Pairs, Mouse Alternative Names

Cd87 qPCR Primer Pairs, Mouse;u-PAR qPCR Primer Pairs, Mouse;uPAR qPCR Primer Pairs, Mouse

uPAR Background Information

Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and uPA levels in both resected tumor tissue and plasma are of independent prognostic significance for patient survival in several types of human cancer. This system has classically been thought to drive tumor progression by mediating directed extracellular proteolysis on the surface of migrating or invading cells, and intervening with this proteolysis by targeting uPAR has been proposed to represent a novel approach for inhibiting tumor progression. uPAR, also known as PLAUR or CD87, has been implicated in the growth, metastasis, and angiogenesis of several solid and hemotologic malignancies. uPAR is a highly glycosylated, 55-6kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. It is part of a cell surface system that also consists of the serine protease uPA and several specific inhibitors (plasminogen activator inhibitors 1 and 2). Additionally, the analysis of CD87 (urokinase-type plasminogen activator receptor - uPAR) expression has a potential role in the diagnostic or prognostic work-up of several hematological malignancies, particularly acute leukemia and multiple myeloma.
Full Name
plasminogen activator, urokinase receptor
References
  • Romer J, et al. (2004) The urokinase receptor as a potential target in cancer therapy. Curr Pharm Des. 10(19): 2359-76.
  • Bn MC, et al. (2004) CD87 (urokinase-type plasminogen activator receptor), function and pathology in hematological disorders: a review. Leukemia. 18(3): 394-400.
  • Pillay V, et al. (2007) The urokinase plasminogen activator receptor as a gene therapy target for cancer. Trends Biotechnol. 25(1): 33-9.
  • Mazar AP. (2008) Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy. Clin Cancer Res. 14(18): 5649-55.
  • uPAR qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    uPAR cDNA ORF Clone in Cloning Vector, Mouse MG50160-M
    uPAR cDNA ORF Clone, Mouse, untagged MG50160-UT
    uPAR Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50160-ACGLN
    uPAR cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50160-ACG
    uPAR cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50160-ACR
    uPAR cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50160-CF
    uPAR cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50160-NF
    uPAR cDNA ORF Clone, Mouse, C-His tag MG50160-CH
    uPAR cDNA ORF Clone, Mouse, N-His tag MG50160-NH
    uPAR cDNA ORF Clone, Mouse, C-HA tag MG50160-CY
    uPAR cDNA ORF Clone, Mouse, N-HA tag MG50160-NY
    uPAR cDNA ORF Clone, Mouse, C-Myc tag MG50160-CM
    uPAR cDNA ORF Clone, Mouse, N-Myc tag MG50160-NM

    uPAR qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    uPAR cDNA ORF Clone in Cloning Vector, Human HG10925-M
    uPAR cDNA ORF Clone, Human, untagged HG10925-UT
    uPAR cDNA ORF Clone, Human, C-GFPSpark® tag HG10925-ACG
    uPAR Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10925-ACGLN
    uPAR cDNA ORF Clone, Human, C-OFPSpark® tag HG10925-ACR
    uPAR cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10925-CF
    uPAR cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10925-NF
    uPAR cDNA ORF Clone, Human, C-His tag HG10925-CH
    uPAR cDNA ORF Clone, Human, N-His tag HG10925-NH
    uPAR cDNA ORF Clone, Human, C-HA tag HG10925-CY
    uPAR cDNA ORF Clone, Human, N-HA tag HG10925-NY
    uPAR cDNA ORF Clone, Human, C-Myc tag HG10925-CM
    uPAR cDNA ORF Clone, Human, N-Myc tag HG10925-NM
    info info
    添加购物车成功! 添加购物车失败!