NPC2 cDNA ORF Clone in Cloning Vector, Rat

Cat: RG80706-U

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NPC2 cDNA ORF Clone in Cloning Vector, Rat General Information

Gene

Species
Rat
NCBI Ref Seq
RefSeq ORF Size
459 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 93C>T, 105C>A and 132G>A not causing the amino acid variation.
Description
Full length Clone DNA of Rat Niemann-Pick disease, type C2.

Plasmid

Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.

Screening

Antibiotic in E.coli
Ampicillin

Storage & Shipping

Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

NPC2 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

NPC2 cDNA ORF Clone in Cloning Vector, Rat Validated Images

Cynomolgus GEMIN8 Gene Plasmid Map 7146

NPC2 Background Information

Niemann-Pick Type C2 (NPC2) plays an important role in the regulation of intracellular cholesterol homeostasis via direct binding with free cholesterol. NPC2 is an intralysosomal protein that binds cholesterol in vitro. NPC2 is a small lysosomal glycoprotein that binds cholesterol with submicromolar affinity. Deficiency in NPC2 is the cause of Niemann-Pick type C2 disease, a fatal neurovisceral disorder characterized by accumulation of cholesterol in lysosomes.Niemann-Pick disease, type C2 (NPC2) protein is one of the most abundant components of the epididymal fluid and contains a functional cholesterol-binding site that can transfer cholesterol between membranes, it has been suggested for years that NPC2 could be involved in the regulation of cholesterol levels in spermatozoa during epididymal maturation.
Full Name
Niemann-Pick disease, type C2

NPC2 cDNA ORF Clone, Rat, Related Products

Product Name Catalog#(PDF)
NPC2 cDNA ORF Clone, Rat, untagged RG80706-UT
NPC2 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80706-ACGLN
NPC2 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80706-ACG
NPC2 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80706-ACR
NPC2 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80706-CF
NPC2 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80706-NF
NPC2 cDNA ORF Clone, Rat, C-His tag RG80706-CH
NPC2 cDNA ORF Clone, Rat, N-His tag RG80706-NH
NPC2 cDNA ORF Clone, Rat, C-HA tag RG80706-CY
NPC2 cDNA ORF Clone, Rat, N-HA tag RG80706-NY
NPC2 cDNA ORF Clone, Rat, C-Myc tag RG80706-CM
NPC2 cDNA ORF Clone, Rat, N-Myc tag RG80706-NM
NPC2 qPCR Primer Pairs, Rat RP300670

NPC2 cDNA ORF Clone, Mouse, Related Products

Product Name Catalog#(PDF)
NPC2 cDNA ORF Clone in Cloning Vector, Mouse MG52313-U
NPC2 cDNA ORF Clone, Mouse, untagged MG52313-UT
NPC2 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG52313-ACGLN
NPC2 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG52313-ACG
NPC2 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG52313-ACR
NPC2 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG52313-CF
NPC2 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG52313-NF
NPC2 cDNA ORF Clone, Mouse, C-His tag MG52313-CH
NPC2 cDNA ORF Clone, Mouse, N-His tag MG52313-NH
NPC2 cDNA ORF Clone, Mouse, C-HA tag MG52313-CY
NPC2 cDNA ORF Clone, Mouse, N-HA tag MG52313-NY
NPC2 cDNA ORF Clone, Mouse, C-Myc tag MG52313-CM
NPC2 cDNA ORF Clone, Mouse, N-Myc tag MG52313-NM
NPC2 qPCR Primer Pairs, Mouse MP202186

NPC2 cDNA ORF Clone, Human, Related Products

Product Name Catalog#(PDF)
NPC2 cDNA ORF Clone in Cloning Vector, Human HG13341-G
NPC2 cDNA ORF Clone, Human, untagged HG13341-UT
NPC2 cDNA ORF Clone, Human, C-GFPSpark® tag HG13341-ACG
NPC2 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG13341-ACGLN
NPC2 cDNA ORF Clone, Human, C-OFPSpark® tag HG13341-ACR
NPC2 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG13341-CF
NPC2 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG13341-NF
NPC2 cDNA ORF Clone, Human, C-His tag HG13341-CH
NPC2 cDNA ORF Clone, Human, N-His tag HG13341-NH
NPC2 cDNA ORF Clone, Human, C-HA tag HG13341-CY
NPC2 cDNA ORF Clone, Human, N-HA tag HG13341-NY
NPC2 cDNA ORF Clone, Human, C-Myc tag HG13341-CM
NPC2 cDNA ORF Clone, Human, N-Myc tag HG13341-NM
NPC2 qPCR Primer Pairs, Human HP102046
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