PXN (Protein | Antibody | cDNA Clone | ELISA Kit)

All PXN reagents are produced in house and quality controlled, including 1 PXN Antibody, 30 PXN Gene, 1 PXN qPCR. All PXN reagents are ready to use.

PXN Background

PXN was significantly upregulated in cervical cancer, which associated with tumor stage, poor differentiation, lymphovascular space invasion and lymphatic metastasis. Knockdown of PXN notably impaired cellular growth and colony formation by suppressing Bcl-2 and inducing marked apoptosis. Moreover, PXN led to resistance to radiation, and downregulation of PXN resensitized C33A cells to radiation.PXN was frequently upregulated and acted as an oncogene via regulating Bcl-2 in cervical cancer, which supports PXN as a potent therapeutic target.