**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-RBP4 rabbit monoclonal antibody at 1:500 dilution
Lane A: HepG2 Whole Cell LysateLysates/proteins at 30 μg per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.
Performed under reducing conditions.Predicted band size:23 kDa
Observed band size:23 kDa
Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM).
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-RBP4 Antibody (FITC)||Rabbit||Monoclonal||FCM||50170-R008-F|
|Anti-RBP4 Antibody (PE)||Mouse||Monoclonal||FCM||10354-MM15-P|
|Anti-RBP4 Antibody (FITC)||Mouse||Monoclonal||FCM||10354-MM15-F|