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TNF-alpha / TNFA / TNFSF2 Anticuerpo, Mabs de conejo

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    Ratón TNFa Información de producto de anticuerpo
    Inmunogen:Recombinant Mouse TNF-alpha / TNFa protein (Catalog#50349-MNAE)
    Clone ID:009
    Tipo de Ig:Rabbit IgG
    Concentración:
    Endotoxina:
    Formulación:0.2 μm filtered solution in PBS
    Preparación:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNF-alpha / TNFa (rM TNF-alpha / TNFa; Catalog#50349-MNAE; NP_038721.1; Leu 80-Leu 235).
    Other TNFa Antibody Products

    Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

    Lane A: NIH3T3 Whole Cell Lysate

    Lane B: Hela Whole Cell Lysate

    Lysates/proteins at 30 μg per lane.

    Secondary

    Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size:15 kDa

    Observed band size:17 kDa

    TNF-alpha/TNFA/TNFSF2 Fondo

    Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

    TNF-alpha Protein & Antibody

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Ratón TNF-alpha/TNFA/TNFSF2 Referencias
  • Hector J, et al. (2007) TNF-alpha alters visfatin and adiponectin levels in human fat. Horm Metab Res. 39(4): 250-5.
  • Berthold-Losleben M, et al. (2008) The TNF-alpha System: Functional Aspects in Depression, Narcolepsy and Psychopharmacology. Curr Neuropharmacol. 6(3): 193-202.
  • Product nameProduct name
    Size / Price
    Catálogo: 50349-R009-50
    Precio de lista: 
    Precio:      (You Save: )
    Tamaño:
    50 µg
    100 µg
    Cantidad:+-
    DisponibilidadIn Stock
    Añadir a carroBulk Discount Requiry

    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Nota: Todos los productos son "PARA SU USO ÚNICAMENTE EN INVESTIGACIÓN Y NO INDICADOS PARA SU USO DIAGNÓSTICO O TERAPÉUTICO"