EGFL6: EGFL6 Protein | EGFL6 Antibody

EGFL6 Background

EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. EGFL6 gene is expressed early during development, and its expression has been detected in lung and meningioma tumors.

Reference for EGFL6

  • Kimura K. et al., 2006, Genome Res. 16 (1): 55-65.
  • Lee SH. et al., 2008, Pathology. 40 (1): 95-7.
  • Oberauer R. et al., 2010, Mol Cell Biochem. 343 (1-2): 257-69.

EGFL6 Protein

EGFL6 protein function

May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). {ECO:0000250}.

EGFL6 protein expression

Induction

Only detected in fetal tissues.

EGFL6 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    553.00
  • Mass (Da)
    61.00

EGFL6 Antibody

There are 2 EGFL6 antibodies which are validated in multiple tissues with various applications, including ELISA. There are 2 EGFL6 antibody for ELISA. Among all these EGFL6 antibodies, there are 2 anti-EGFL6 rabbit polyclonal antibodies . All the EGFL6 anbodies are produced in house and all are in stock. EGFL6 antibody customerized service is available.

EGFL6 Gene

EGFL6 gene / cDNA is a protein-coding gene which located on Xp22.2. The EGFL6 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.225 organisms have orthologs with human gene EGFL6.